anti-NID1 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-NID1 antibody; NID1; Nidogen;
The NID1 nid1 (Catalog #MBS602420) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Nidogen (Entactin) G2 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Nidogen can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Western blot: Recognizes native and denatured nidogen., This antibody is able to block the binding of nidogen to laminin., ELISA. Researchers should empirically determine the suitability of the NID1 nid1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NID1 nid1 product has the following accession number(s) (GI #189209) (Uniprot Accession #P14543). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The extracellular matrix is a complex network of secreted (glyco)proteins situated in between cells of particular types of tissue. The relative amounts of the different types of matrix macromolecules and the way in which they are organized in the extracellular matrix vary between different tissues. For example, connective tissues have extensive extracellular matrices in which fibrous polymers, especially collagen, are present. In contrast, in epithelial tissues the extracellular matrix consists only of a thin mat called the basal lamina, which underlies the epithelial cell sheet. Cells located in the extracellular matrix produce matrix constituents and control the organization of these matrix components. The main components of the extracellular matrix are proteoglycans (e.g. aggrecan, perlecan and syndecan) and fibrous proteins (e.g. collagen, elastin, fibronectin and laminin). The extracellular matrix, next to being a scaffold to support cells in a particular tissue, also plays a role in the regulation of processes such as proliferation, differentiation, adhesion and locomotion of these cells.
Immunogen: Recombinant fragment corresponding to the G2 region of mouse nidogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NID1 are readily searchable from our website. Different antibodies against the same target such as NID1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Heart, Kidney, Lung, Skin, Spleen, Stomach tissues are correlated with this protein. NID1 also interacts with the following gene(s): COL4A1, HSPG2.