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anti-NFKBIE antibody product blog

Posted on 2014-03-14 15:42:28 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-NFKBIE antibody; NFKBIE; IkB-epsilon;
The NFKBIE nfkbie (Catalog #MBS857684) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IkB-epsilon (Ab-22) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s IkB-epsilon can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
WB: 1:500~1:1000, IHC: 1:50~1:100. Researchers should empirically determine the suitability of the NFKBIE nfkbie for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The NFKBIE nfkbie product has the following accession number(s) (GI #71274109) (NCBI Accession #NP_004547.2) (Uniprot Accession #O00221). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IkB-epsilon (Ab-22) Antibody with the following immunoassay(s):
Testing Data (Peptide - +
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-epsilon (Ab-22) antibody (E021296).)
Testing Data NFKBIE.

Testing Data #2 (Western blot analysis of extract from 293 cells, untreated or treated with TNF-alpha (20ng/ml, 15min), using IkB-epsilon (Ab-22) antibody and IkB-epsilon (Phospho-Ser22) antibody (E011213, Lane 3 and 4).)
Testing Data #2 NFKBIE.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human IkB-epsilon around the phosphorylation site of serine 22 (I-E-SP-L-R).
Pathway: NF-kappa B, Cancer/Apoptosis. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NFKBIE are readily searchable from our website. Different antibodies against the same target such as NFKBIE may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arthritis, Rheumatoid, Atherosclerosis, Cell Transformation, Neoplastic, Edema, Inflammation, Kidney Diseases, Lung Diseases, Necrosis, Neoplasms, Experimental, Pneumonia are some of the diseases may be linked to IkB-epsilon (Ab-22) Antibody. NFKBIE also interacts with the following gene(s): CHUK, IKBKB, NFKB1, NFKB2, REL, RELA, RELB. The following patways have been known to be associated with this gene. Blood, Bone, Intestine, Kidney, Lung, Lymph Node, Pancreas, Spleen, Testis, Vascular tissues are correlated with this protein.
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