anti-MSH alpha antibody product blog
Tags: Antibody; Polyclonal Antibody; MSH alpha; anti-MSH alpha antibody;
The MSH alpha n/a (Catalog #MBS619008) is an Antibody produced from Guinea pig and is intended for research purposes only. The product is available for immediate purchase. The MSH alpha (Melanocyte Stimulating Hormone alpha) reacts with Human, Sheep and may cross-react with other species as described in the data sheet. MyBioSource\'s MSH alpha can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry: 1:2000
No staining is evident when the primary antibody is pre-absorbed with 0.5mg/ml of alpha MSH. Cells are stained when the primary antibody is pre-absorbed with 0.5mg/ml of beta MSH or 0.5mg/ml of gamma MSH.
Optimal dilution determined by the researcher. Researchers should empirically determine the suitability of the MSH alpha n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MSH alpha n/a product has the following accession number(s) (GI #444638). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the MSH alpha (Melanocyte Stimulating Hormone alpha) with the following immunoassay(s):
Testing Data (Staining of cells in sheep hypothalamus using MBS619008 (1:1000) followed by incubation with FITC labeled goat anti-guinea pig secondary antibodies.)
Proopiomelanocortin (POMC) is the precursor of the melanocortin peptides alpha, beta and gamma. POMC neurons in the arcuate nucleus of the hypothalamus function as key central regulators of food intake and homeostatic control of energy balance in both rodents and non-human primates. MSH increases the pigmentation of skin by increasing the melanin production in melanocytes. MSH is produced in the pituitary gland and belongs to the POMC family.
Immunogen: A synthetic peptide corresponding to the antigenic region within the human alpha MSH residue. Conjugated to carrier protein. Positive Control: Sheep brain (hypothalamus). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MSH alpha are readily searchable from our website. Different antibodies against the same target such as MSH alpha may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.