anti-MEP1A antibody product blog
Tags: Antibody; Polyclonal Antibody; Meprin A, alpha; anti-MEP1A antibody; MEP1A;
The MEP1A mep1a (Catalog #MBS617429) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The Meprin A, alpha (MEP1A, PABA Peptide Hydrolase) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Meprin A, alpha can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC).Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:250. Researchers should empirically determine the suitability of the MEP1A mep1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MEP1A mep1a product has the following accession number(s) (GI #153070262) (NCBI Accession #NP_005579.2) (Uniprot Accession #Q16819). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Meprin A, alpha (MEP1A, PABA Peptide Hydrolase) with the following immunoassay(s):
Western Blot (WB) (Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.)
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. Mature meprins are oligomers of evolutionarily related, separately encoded alpha and/or beta subunits. Homooligomers of meprin-alpha (MEP1A; MIM 600388) are secreted; oligomers containing meprin-beta are associated with the plasma membrane. Substrates include bioactive peptides and extracellular matrix proteins.
Immunogen: Synthetic peptide corresponding to aa594-694 of human MEP1A. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MEP1A are readily searchable from our website. Different antibodies against the same target such as MEP1A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Colitis, Inflammation, Kidney Diseases, Nervous System Diseases are some of the diseases may be linked to Meprin A, alpha (MEP1A, PABA Peptide Hydrolase). MEP1A also interacts with the following gene(s): MEP1B. Intestine tissues are correlated with this protein.