|The MDK mdk (Catalog #MBS535798) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Midkine antibody reacts with Human midkine and may cross-react with other species as described in the data sheet. MyBioSource\'s Midkine can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the MDK mdk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The MDK mdk product has the following accession number(s) (GI #59894796) (NCBI Accession #NP_001012333.1) (Uniprot Accession #P21741). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Rabbit polyclonal Midkine antibody.
Biological Significance: Midkine (MK) and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Immunogen: Midkine antibody was raised in rabbit using highly pure recombinant human Midkine as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MDK are readily searchable from our website. Different antibodies against the same target such as MDK may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Lymph Node, Muscle tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Carcinoma, Hepatocellular, Disease Models, Animal, Inflammation, Kidney Diseases, Neoplasms, Experimental, Nervous System Diseases, Pain, Skin Diseases are some of the diseases may be linked to Midkine antibody. MDK also interacts with the following gene(s): ACE, STAT1. The following patways have been known to be associated with this gene.