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anti-MC2R antibody product blog

Posted on 2015-07-10 17:56:46 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; MC2R/ACTHR; anti-MC2R antibody; MC2R ;
The MC2R mc2r (Catalog #MBS420719) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-MC2R/ACTHR Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. MyBioSource\'s MC2R/ACTHR can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB).
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 40kDa band observed in Human Skin lysates (calculated MW of 33.9kDa according to NP_000520.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Kilianova et al, Endocrinology.2006 May;147(5): 2325-37; PMID: 16497811). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the MC2R mc2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The MC2R mc2r product has the following accession number(s) (GI #4505127) (NCBI Accession #NP_000520.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat anti-MC2R/ACTHR Antibody with the following immunoassay(s):
Western Blot (WB) ((1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB) MC2R.

Immunogen: Peptide with sequence ENINNTARNNSDC, from the N Terminus of the protein sequence according to NP_000520.1.
Epitope: N Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing MC2R are readily searchable from our website. Different antibodies against the same target such as MC2R may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adrenal Gland, Brain tissues are correlated with this protein. The following patways have been known to be associated with this gene. Adenocarcinoma, Cardiovascular Diseases, Death, Disease Models, Animal, Familial Glucocorticoid Deficiency 1, Hyperplasia, Hypertension, Inflammation, Prenatal Exposure Delayed Effects, Urogenital Abnormalities are some of the diseases may be linked to Goat anti-MC2R/ACTHR Antibody.
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