|The lep n/a (Catalog #MBS535071) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Leptin antibody reacts with Human leptin and may cross-react with other species as described in the data sheet. MyBioSource\'s Leptin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the lep n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The lep n/a product has the following accession number(s) (GI #148233267) (NCBI Accession #NP_001089183.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Rabbit polyclonal Leptin antibody.
Biological Significance: Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Immunogen: Leptin antibody was raised in rabbit using highly pure recombinant human leptin as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing lep are readily searchable from our website. Different antibodies against the same target such as lep may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.