anti-KDM4A antibody product blog
Tags: Antibody; JMJD2A; Polyclonal Antibody; anti-KDM4A antibody; KDM4A;
The KDM4A kdm4a (Catalog #MBS150247) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JMJD2A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s JMJD2A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC).JMJD2A antibody can be used for detection of JMJD2A by Western blot at 1 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. Researchers should empirically determine the suitability of the KDM4A kdm4a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The KDM4A kdm4a product has the following accession number(s) (GI #55665236) (NCBI Accession #CAH71021) (Uniprot Accession #O75164). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the JMJD2A Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of JMJD2A in rat liver tissue lysate with JMJD2A antibody at (A) 1 and (B) 2 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of JMJD2A in rat liver tissue with JMJD2A antibody at 5 μg/mL.)
JMJD2A Antibody: Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. The first member of this group, JMJD2A, is widely expressed in human tissues and cell lines and functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. JMJD2A can also form a complex with the androgen receptor (AR), a transcription factor that is pivotal for the development of prostate cancer. Overexpression of JMJD2A stimulates AR function and this stimulation is dependent on JMJD2A catalytic activity, suggesting that JMJD2A might be a critical protein with roles in cell proliferation and oncogenesis.
Conjugate: Unconjugated
Immunogen: JMJD2A antibody was raised against a 14 amino acid synthetic peptide from near the center of human JMJD2A.
Buffer: JMJD2A Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing KDM4A are readily searchable from our website. Different antibodies against the same target such as KDM4A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.