anti-ISL1 antibody product blog
Tags: Antibody; Monoclonal Antibody; ISL1; anti-ISL1 antibody;
The ISL1 isl1 (Catalog #MBS850276) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ISL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ISL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
IF: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the ISL1 isl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ISL1 isl1 product has the following accession number(s) (GI #115387114) (NCBI Accession #NP_002193.2) (Uniprot Accession #P61371). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ISL1 Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1. Western blot analysis using MYL3 (1) and MYL2 (2) mouse mAb against rat fetal heart tissues lysate.)
Immunohistochemistry (IHC) (Figure 2. Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and cervical carcinoma (right), showing nuclear localization using ISL1 mouse mAb with DAB staining.)
Immunohistochemistry (IHC) (Figure 3. Immunohistochemical analysis of paraffin-embedded human Heart tissues using MYL3 mouse mAb.)
ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Immunogen: Purified recombinant fragment of human ISL1 expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ISL1 are readily searchable from our website. Different antibodies against the same target such as ISL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Cardiovascular Abnormalities, Cardiovascular Diseases, Congenital Abnormalities, Fibrosis, Heart Defects, Congenital, Heart Diseases, Lung Neoplasms, Neoplasm Metastasis, Nervous System Diseases are some of the diseases may be linked to ISL1 Antibody.