anti-INSM1 antibody product blog
Tags: Antibody; Polyclonal Antibody; IA-1; anti-INSM1 antibody; INSM1;
The INSM1 insm1 (Catalog #MBS151328) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IA-1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s IA-1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).IA-1 antibody can be used for detection of IA-1 by Western blot at 1 mug/mL. Researchers should empirically determine the suitability of the INSM1 insm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The INSM1 insm1 product has the following accession number(s) (GI #4504713) (NCBI Accession #NP_002187) (Uniprot Accession #Q01101). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IA-1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of IA-1 in rat thymus tissue lysate with IA-1 antibody at 1 μg/mL.)
IA-1 Antibody: IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.
Conjugate: Unconjugated
Immunogen: IA-1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1.
Buffer: IA-1 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INSM1 are readily searchable from our website. Different antibodies against the same target such as INSM1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Brain Diseases, Death, Hemorrhage, Liver Diseases, Liver Neoplasms, Neoplasms, Experimental, Seizures are some of the diseases may be linked to IA-1 Antibody.