anti-INS antibody product blog
Tags: Antibody; INS; Polyclonal Antibody; anti-INS antibody; Insulin + Proinsulin;
The INS ins (Catalog #MBS535247) is an Antibody produced from Guinea Pig and is intended for research purposes only. The product is available for immediate purchase. The Insulin + Proinsulin antibody reacts with Hamster, Human, Pig, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Insulin + Proinsulin can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin/Paraffin.IF-PAP: 1:3,000-1:5,000
IF-FITC: 1:1,000-1:2,000. Researchers should empirically determine the suitability of the INS ins for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The INS ins product has the following accession number(s) (GI #4557671) (NCBI Accession #NP_000198.1) (Uniprot Accession #P01308). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Guinea Pig polyclonal Insulin + Proinsulin antibody.
Biological Significance: Insulin is a hormone central to regulating carbohydrate and fat metabolism in the body. Insulin causes cells in the liver, muscle, and fat tissue to take up glucose from the blood, storing it as glycogen in the liver and muscle. Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene. Cross-Reactivity: Hamster, human, pig, rat
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: Insulin/Proinsulin antibody was raised in guinea pig using synthetic human proinsulin as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INS are readily searchable from our website. Different antibodies against the same target such as INS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Diabetes Mellitus, Diabetes Mellitus, Type 2, Hyperglycemia, Hyperinsulinism, Hypertension, Hypoglycemia, Insulin Resistance, Metabolic Diseases, Obesity, Polycystic Ovary Syndrome are some of the diseases may be linked to Insulin + Proinsulin antibody. INS also interacts with the following gene(s): AKT1, FOXO1, IGF1R, IGFBP1, INSR, IRS1, IRS2, PDX1. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Heart, Kidney, Liver, Muscle, Nerve, Pancreas, Vascular tissues are correlated with this protein.