anti-INS antibody product blog
Tags: Antibody; Insulin; INS; Polyclonal Antibody; anti-INS antibody;
The INS ins (Catalog #MBS373028) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Insulin reacts with Human, Canine, Feline, Rat and may cross-react with other species as described in the data sheet.The INS ins product has the following accession number(s) (GI #386828) (NCBI Accession #AAA59172.1) (Uniprot Accession #P01308). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Insulin with the following immunoassay(s):
Dilution Information
Immunohistochemistry (IHC)
Insulin is produced in the beta cells of the Islets of Langerhans in the pancreas. It is a polypeptide hormone that regulates carbohydrate metabolism. Apart from being the primary agent in carbohydrate homeostasis, insulin has effects on fat metabolism and changes the liver\'s ability in storing or releasing glucose and processing blood lipids, and in other tissues such as fat and muscle. The amount of insulin in circulation has extremely widespread effects throughout the body. The presence of insulin in the cytoplasm of Islet Tumors is the most reliable indication of functional Insulinomas. Defective insulin storage occurs in Insulinomas; therefore, many sections of the tumor should be stained with both insulin and C-peptide.
Control: Pancreas
Localization: Cytoplasmic. Reactivity Note: Paraffin, Frozen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INS are readily searchable from our website. Different antibodies against the same target such as INS may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Heart, Kidney, Liver, Muscle, Nerve, Pancreas, Vascular tissues are correlated with this protein. INS also interacts with the following gene(s): GCK, HLA-DQB1, IDE, IGF1R, INSR, SYTL4. Adenoma, Cardiovascular Diseases, Diabetes Mellitus, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Insulin Resistance, Kidney Diseases, Kidney disorder involving deposition of calcium and oxalate or phosphate in the renal tubules, Neoplasms, Pancreatic Neoplasms are some of the diseases may be linked to Insulin. The following patways have been known to be associated with this gene.