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anti-INPP5D antibody product blog

Posted on 2013-12-05 01:15:08 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; SHIP; anti-INPP5D antibody; INPP5D;
The INPP5D inpp5d (Catalog #MBS625892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SHIP, ID (INPP5D, SH2-containing Inositol 5-phosphatase 1, SH2 Domain-containing Inositol Phosphatase 1, SHIP-1, Inositol Polyphosphate-5-phosphatase of 145kD, SIP-145, p150Ship Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1, hp51CN, SHIP1) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SHIP can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the INPP5D inpp5d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The INPP5D inpp5d product has the following accession number(s) (GI #1888525) (NCBI Accession #AAB49680.1) (Uniprot Accession #Q92835). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and it is a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5\' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival.

INPP5D inpp5d

Immunogen: Synthetic peptide selected from the Center region of human INPP5D (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INPP5D are readily searchable from our website. Different antibodies against the same target such as INPP5D may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone Marrow, Brain, Heart, Lymph, Lymph Node, Spleen tissues are correlated with this protein. The following patways have been known to be associated with this gene. INPP5D also interacts with the following gene(s): GRB2. Carcinoma, Death, Fatty Liver, Fibrosis, Inflammation, Liver Cirrhosis, Liver Diseases, Necrosis, Neoplasms, Nervous System Diseases are some of the diseases may be linked to SHIP, ID (INPP5D, SH2-containing Inositol 5-phosphatase 1, SH2 Domain-containing Inositol Phosphatase 1, SHIP-1, Inositol Polyphosphate-5-phosphatase of 145kD, SIP-145, p150Ship Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1, hp51CN, SHIP1).
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