anti-INHA antibody product blog
Tags: Antibody; INHA; Monoclonal Antibody; anti-INHA antibody;
The INHA inha (Catalog #MBS850735) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The INHA (Inhibin alpha) Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s INHA (Inhibin alpha) can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA (EIA).IF: 1:200-1:1000
IHC: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the INHA inha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The INHA inha product has the following accession number(s) (GI #4504697) (NCBI Accession #NP_002182.1) (Uniprot Accession #P05111). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the INHA (Inhibin alpha) Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Figure 1. Immunohistochemical analysis of paraffin-embedded human lymphoid (A), ovary tumor (B) and testicle tumor (C) tissues using INHA mouse mAb with DAB staining.)
Immunofluorescence (IF) (Figure 2. Confocal immunofluorescence analysis of Hela cells using INHA mouse mAb (green). Red. Actin filaments have been labeled with DY-554 phalloidin. Blue. DRAQ5 fluorescent DNA dye.)
INHA (A-inhibin subunit precursor, inhibin alpha subunit), also called inhibin (alpha), which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits, Inhibin An and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal, bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.
Immunogen: Purified recombinant fragment of human INHA expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INHA are readily searchable from our website. Different antibodies against the same target such as INHA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.