Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Blog  rightarrow anti-INCENP antibody  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-F8 antibody blog
 • Caspase 3 Inhibitor, Z-DEVD-FMK inhibitor blog
 • LRP5 recombinant protein blog
 • Bis-dPEG17-NHS reagent blog
 • Indolicidin peptide blog
 • anti-Ceftiofur (includes BSA conjugate) antibody blog
 • anti-IgG2a antibody blog
 • anti-CD86 antibody blog
 • ARHGEF10L shrna blog
 • SRAGE elisa kit blog
 • CCIN sirna blog
 • AP/3a-5a-THP elisa kit blog
 • HAND2 shrna blog
 • p130 peptide blog
 • RPS3A shrna blog
 • DLX3 sirna blog
 • PANCREASTATIN elisa kit blog
 • ECEL1 sirna blog
 • anti-Tnnt2 antibody blog
 • SLC6A11 sirna blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • ADIPOQ Antibody
 • EZR cDNA Clone
 • Transcription Factor IIB (C16orf80) Antibody
 • fatty acid binding protein 1, liver (FABP1) ELISA Kit
 • AID (AICDA) Antibody
 • LRP5 (Non-phospho) (LRP5 (Non-phospho)) Antibody
 • Listeria monocytogenes Antibody
 • CD1C Antibody
 • FK506 binding protein 5 (Fkbp5) ELISA Kit
 • Transketolase 1 (tktA) Recombinant Protein
 • Myelin Basic Protein (Mbp) Antibody
 • Anguilla anguilla (European Eel) PCR Kit
 • Beta-Defensins 2 (DEFbeta2) ELISA Kit
 downarrow more ...

anti-INCENP antibody product blog

Posted on 2013-07-20 19:37:35 by mybiosource_staff
Share it on ...     
Tags: Antibody; Polyclonal Antibody; INCENP; anti-INCENP antibody;
The INCENP incenp (Catalog #MBS610766) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INCENP (Incenp, Inner Centromere Protein) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s INCENP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FC/FACS), Immunofluorescence (IF).
Suitable for use in Immunofluorescence, Flow Cytometry and Western Blot.
Dilution: Immunofluorescence: 1:400
Flow Cytometry: 1:50
Western Blot: 1:1000. Researchers should empirically determine the suitability of the INCENP incenp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The INCENP incenp product has the following accession number(s) (GI #102467242) (NCBI Accession #NP_064623.2) (Uniprot Accession #Q9NQS7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

INCENP (inner centromere protein antigens 135kD, 155kD) is a chromosomal passenger protein crucial for multiple events that mediate chromosome separation during mitosis (1). At prophase INCENP is associated with chromatin whereas during prometaphase and metaphase it translocates to the inner centromere (1). Depletion of INCENP results in aberrant chromosome alignment at the metaphase plate, incomplete chromosome separation, and disruption of proper spindle formation and cytokinesis (2). INCENP is part of the chromosomal passenger complex that also contains Aurora B, borealin and survivin (2). Aurora B and INCENP are mutually dependent on each other for proper localization (3), and in Drosophila cells and C.elegans embryos that lack INCENP or survivin, Aurora B cannot organize the kinetochores and the midbody (4,5). Phosphorylation on INCENP by CDK1 on Thr59 and Thr388 leads to the association of INCENP with Plk1, another important regulator of mitotic entry and exit (6). Interaction of INCENP with Plk1 is necessary for recruitment of Plk1 to the kinetochores, and the metaphase to anaphase transition (6). Interactions have also been reported between INCENP and heterochromatin protein 1 (HP1) (7) and -tubulin (8).

INCENP incenp

Immunogen: Synthetic peptide (KLH-coupled) corresponding to amino acids surrounding Pro240 of human INCENP. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing INCENP are readily searchable from our website. Different antibodies against the same target such as INCENP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. INCENP also interacts with the following gene(s): AURKB, BIRC5, CDCA8.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions