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anti-IL37 antibody product blog

Posted on 2014-08-01 20:53:24 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; IL-37; anti-IL37 antibody; IL37;
The IL37 il37 (Catalog #MBS646331) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s IL-37 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC).
Suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Recommended Dilution:

ELISA; 1:2000-1:5000
Wester Blot: 1:2000-1:5000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20, 5% skim milk,; suggested incubation time is 1 hour at RT
Immunohistochemistry: 1:50
Immunoprecipitation: 1:500-1:2000
Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the IL37 il37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The IL37 il37 product has the following accession number(s) (GI #27894302) (NCBI Accession #NP_775297.1) (Uniprot Accession #Q9NZH6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IL-37 (Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1) with the following immunoassay(s):
Western blot (Western blot analysis)
Western blot IL37.

Immunoprecipitation (Immunoprecipitation of human IL-37)
Immunoprecipitation IL37.

Immunohistochemical (Immunohistochemical staining of IL-37 in human rheumatoid arthritis tissue )
Immunohistochemical IL37.

Immunohistochemical staining (IHC staining of IL-37 in human kidney (A 1), human colon (B 1), human skin (C) and human stomach (D) using MBS646331. Human kidney (A2) and human colon (B2) are stained with negative control anti-rabbit IgG.)
Immunohistochemical staining IL37.

IL-37 (Interleukin-37) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth.

Immunogen: Recombinant human IL-37. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL37 are readily searchable from our website. Different antibodies against the same target such as IL37 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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