anti-IL27 antibody product blog
Tags: Antibody; IL27; Polyclonal Antibody; IL-27; anti-IL27 antibody;
The IL27 il27 (Catalog #MBS150576) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL-27 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s IL-27 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).IL-27 antibody can be used for the detection of IL-27 by Western blot at 2 - 4 mug/mL. Researchers should empirically determine the suitability of the IL27 il27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL27 il27 product has the following accession number(s) (GI #28416913) (NCBI Accession #NP_663634) (Uniprot Accession #Q8NEV9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the IL-27 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of IL-27 in Daudi lysate with IL-27 antibody at (A) 2 and (B) 4 μg/mL.)
IL-27 Antibody: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of na�ve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.
Conjugate: Unconjugated
Immunogen: IL-27 antibody was raised against a 14 amino acid synthetic peptide from near the center of human IL-27.
Buffer: IL-27 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL27 are readily searchable from our website. Different antibodies against the same target such as IL27 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Arthritis, Experimental, Colitis, Death, Diabetes Mellitus, Type 1, Encephalomyelitis, Autoimmune, Experimental, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Necrosis are some of the diseases may be linked to IL-27 Antibody.