|The IL18BP il18bp (Catalog #MBS535804) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The IL18BP antibody reacts with Murine IL-18BP and may cross-react with other species as described in the data sheet. MyBioSource\'s IL18BP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the IL18BP il18bp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL18BP il18bp product has the following accession number(s) (GI #6754314) (NCBI Accession #NP_034661.1) (Uniprot Accession #Q9Z0M9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Affinity purified Goat polyclonal IL18BP antibody.
Biological Significance: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. Immunogen: IL18BP antibody was raised in goat using highly pure recombinant murine IL-18BP as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL18BP are readily searchable from our website. Different antibodies against the same target such as IL18BP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. IL18BP also interacts with the following gene(s): Il18. Arteriosclerosis, Blood Coagulation Disorders, Heart Diseases, Hyperplasia, Hypertrophy, Infertility, Female, Inflammation, Liver Diseases, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to IL18BP antibody. Lung, Mixed, Skin, Spleen, Thymus, Uterus tissues are correlated with this protein.