|The IL-1b il1b (Catalog #MBS140161) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s IL-1 beta can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC).
Direct ELISA, Western Blot, Immunoprecipitation, immunohistochemistry.
By direct ELISA, 1:20,000 dilution will yield >1.0 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig. 1:2,000 dilution will completely inhibit a thymocyte co-stimulation assay using suboptimal doses of concanavalin A. Researchers should empirically determine the suitability of the IL-1b il1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL-1b il1b product has the following accession number(s) (GI #6680415) (NCBI Accession #NP_032387.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Introduction: Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Reconstitution: Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Note: The antibody was produced in BALB/c mice.
Immunogen: r.Human IL-1b. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL-1b are readily searchable from our website. Different antibodies against the same target such as IL-1b may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. IL-1b also interacts with the following gene(s): Casp1, Il18, Il1a, Il1r1, Il1r2, Il6, Myd88, Nfkb1, Rela, Tnf. Adenocarcinoma, Arthritis, Rheumatoid, Asthma, Colitis, Hypersensitivity, Inflammation, Myocardial Ischemia, Necrosis, Skin Diseases, Stomach Neoplasms are some of the diseases may be linked to Mouse Anti Human IL-1 beta. The following patways have been known to be associated with this gene. Blood, Bone Marrow, Brain, Lung, Lymph Node, Mammary Gland, Muscle, Spleen, Thymus, Vagina tissues are correlated with this protein.