|The IKBKE ikbke (Catalog #MBS625447) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IKK epsilon, phosphorylated (Thr501) (IKKe) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s IKK epsilon can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:2500-1:5000
Western Blot: 1:500. Researchers should empirically determine the suitability of the IKBKE ikbke for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IKBKE ikbke product has the following accession number(s) (GI #300937401) (NCBI Accession #NP_001180251.1) (Uniprot Accession #Q14164). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Nuclear Factor kappa B (NF-kB) is an ubiquitous transcription factor and an essential mediator of gene expression during the activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cytoplasm of the cell, which inhibit NF- B activity. IkB proteins are phosphorylated by an I B kinase complex consisting of at least three proteins, IKKa, IKKb and.
Immunogen: Synthetic phoshopeptide sequence (RSRLRpTLAEVL) corresponding to aa496-506 of human IKKe (KLH coupled). Positive Control: HeLa cells or TNF inducible KBM-5 cells. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IKBKE are readily searchable from our website. Different antibodies against the same target such as IKBKE may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Bone Marrow, Embryonic Tissue, Intestine, Kidney, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. IKBKE also interacts with the following gene(s): AZI2, IRF3, IRF7, MAVS, TANK, TAX1BP1, TBK1, TNFAIP3, UBC. Adenocarcinoma, Atherosclerosis, Carcinoma, Cardiovascular Diseases, Congenital Abnormalities, Disease Models, Animal, Inflammation, Necrosis, Neoplasms, Prostatic Diseases are some of the diseases may be linked to IKK epsilon, phosphorylated (Thr501) (IKKe). The following patways have been known to be associated with this gene.