anti-IGF1R antibody product blog
Tags: Antibody; anti-IGF1R antibody; IGF1R; Monoclonal Antibody; IGF1R / IGF1 Receptor;
The IGF1R igf1r (Catalog #MBS245470) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone JBW902] (IgG2a) to Human IGF1R / IGF1 Receptor reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s IGF1R / IGF1 Receptor can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP).IHC-P (5 ug/ml), IP, WB
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the IGF1R igf1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IGF1R igf1r product has the following accession number(s) (GI #4557665) (NCBI Accession #NP_000866.1) (Uniprot Accession #P08069). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse Monoclonal [clone JBW902] (IgG2a) to Human IGF1R / IGF1 Receptor with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-IGF1 Receptor antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC) (Anti-IGF1 Receptor antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
IGF1R, an insulin receptor type protein kinase, mediates IGF1 stimulated cell proliferation and differentiation. IGF1R binds insulin-like growth factor I with high affinity and IGF II with a lower affinity. The protein has been shown to be highly expressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
Target Species: Human
Immunogen Description: GST fusion protein corresponding to residues 1264-1367 of human IGF-1 Receptor. Immunogen Type: Fusion protein
Immunogen: IGF1R / IGF1 Receptor antibody was raised against gST fusion protein corresponding to residues 1264-1367 of human IGF-1 Receptor.
Antigen Modification: aa1264-1367. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IGF1R are readily searchable from our website. Different antibodies against the same target such as IGF1R may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.