anti-I-Ab (public; Ia.m8) antibody product blog
Tags: Antibody; Monoclonal Antibody; I-Ab (public; Ia.m8); anti-I-Ab (public; Ia.m8) antibody;
The I-Ab (public; Ia.m8) n/a (Catalog #MBS520351) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse I-Ab (public; Ia.m8), Purified (Clone 28-16-8S) (mouse IgM) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s I-Ab (public; Ia.m8) can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Cytotoxic Assay (CA). Researchers should empirically determine the suitability of the I-Ab (public; Ia.m8) n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-Mouse I-Ab (public; Ia.m8), Purified (Clone 28-16-8S) (mouse IgM) with the following immunoassay(s):
Testing Data
anti- I-Ab monoclonal antibody reacts with the I-Ab encoded MHC class II antigen expressed on mouse strains of the H-2b haplotype. It also reacts with the I-Ad encoded MHC class II antigen expressed on mouse strains of the H- 2d haplotype. The reaction pattern of this antibody with a panel of inbred and recombinant haplotypes demonstrates that the antibody detects the public Ia.m8 determinant. Class II antigens are most highly expressed on antigen-presenting cells including B cells, macrophages, dendritic cells and certain epithelial cells. This antibody is suitable for use in flow cytometry and can be used to quantitate or eliminate cells bearing the I-Ab antigen from the appropriate strains of mice.
Immunogen: C3H.SW spleen
Donor: C3H
Fusion Partner: SP2/0Ag.14. Presentation: 250 ug purified Ig buffered in PBS and 0.02% NaN3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing I-Ab (public; Ia.m8) are readily searchable from our website. Different antibodies against the same target such as I-Ab (public; Ia.m8) may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.