anti-HspBP1 antibody product blog
Tags: Antibody; Polyclonal Antibody; HspBP1; anti-HspBP1 antibody;
The HspBP1 hspbap1 (Catalog #MBS440079) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HspBP1 (FL4) Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s HspBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the HspBP1 hspbap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The HspBP1 hspbap1 product has the following accession number(s) (GI #21314714) (NCBI Accession #NP_078886.2) (Uniprot Accession #Q96EW2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the HspBP1 (FL4) Antibody with the following immunoassay(s):
Western Blot (WB)
HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system (1). The ATPase domain of Hsp70 binds HspBP1 and upon binding inhibits Hsp70 chaperone activity. More recently HspBP1 was found to be a homologue of the yeast Fes1 and Sls1 proteins and promotes nucleotide dissociation from Hsc70. HspBP1 has also been shown to strip nucleotide from yeast Ssa1p, making it a member of the class of nucleotide exchange factors that exhibit varying degrees of compartment and species specificity (2). HspBP1 is highly expressed in heart, brain, skeletal muscle, and pancreas tissues. It is also expressed in pancreatic, hepatic, and astrocytic cell lines.
Origin: HspBP1 (FL4) is provided as an affinity purified rabbit polyclonal antibody, raised against a truncation mutant that cotains amino acids 84-359 of human recombinant HspBP1 (3). Immunogen: a truncation mutant that cotains amino acids 84-359 of human recombinant HspBP1 (3).
License: (FL4)HspBP1 is sold under License from Desert Genetics, Inc. under United States Patent 6,410,713. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HspBP1 are readily searchable from our website. Different antibodies against the same target such as HspBP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Chromosome Aberrations, Chromosome Breakage, Kidney Diseases, Liver Cirrhosis, Nervous System Diseases, Seizures are some of the diseases may be linked to HspBP1 (FL4) Antibody.