anti-HSP90B1 antibody product blog
Tags: Antibody; Monoclonal Antibody; HSP90B1; anti-HSP90B1 antibody; Grp94;
The HSP90B1 hsp90b1 (Catalog #MBS190038) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Grp94 can be used in a range of immunoassay formats including, but not limited to, Immunoblot, Immunohistochemistry, Immunoprecipitation.Immunoblotting: use at 0.5-1ug/ml. A band of ~98 kDa is detected.
Immunohistochemistry: use at 2-30ug/ml.
Immunoprecipitation: 10ug/ml.
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: HeLa cell lysate. Researchers should empirically determine the suitability of the HSP90B1 hsp90b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HSP90B1 hsp90b1 product has the following accession number(s) (GI #403497) (Uniprot Accession #P41148). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Glucose-regulated protein 94 (Grp94) is an endoplasmic reticulum luminal stress protein which belongs to the Hsp90 family of molecular chaperones. The sequence of Grp94 includes the COOH-terminal tetrapeptide Lys-Asp-Glu-Leu (KDEL) which is a signal sequence that causes proteins to be retained in the pre-Golgi compartments. Expression of Grp94 is up-regulated by stress conditions such as glucose starvation and heat shock, and it functions in intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen-presenting cells.
Antigen: Purified Grp94 isolated from chicken oviducts. Preservatives: None. Available on request.
Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HSP90B1 are readily searchable from our website. Different antibodies against the same target such as HSP90B1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bipolar Disorder, Carcinoma, Genital Diseases, Male, Immune System Diseases, Inflammation, Male Urogenital Diseases, Multiple Myeloma, Neoplasms, Prostatic Diseases, Schizophrenia are some of the diseases may be linked to Anti-Grp94 Monoclonal Antibody. The following patways have been known to be associated with this gene. Brain, Testis, Thyroid tissues are correlated with this protein.