anti-HLA-A antibody product blog
Tags: Antibody; Monoclonal Antibody; HLA-A; anti-HLA-A antibody; HLA Class 1 Antigen A2,A28;
The HLA-A hla-a (Catalog #MBS603096) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HLA Class 1 Antigen A2,A28 (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s HLA Class 1 Antigen A2,A28 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF).Suitable for use in Immunofluorescence, Flow Cytometry, Cytotoxicity Studies.
Dilution: Flow Cytometry: 10ul/test. Researchers should empirically determine the suitability of the HLA-A hla-a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The HLA-A hla-a product has the following accession number(s) (GI #13124681) (Uniprot Accession #O02860). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The human leukocyte antigen system (HLA) is the name of the major histocompatibility complex (MHC) in humans. The superlocus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and many other genes. The HLA genes are the human versions of the MHC genes that are found in most vertebrates (and thus are the most studied of the MHC genes). The proteins encoded by certain genes are also known as antigens, as a result of their historic discovery as factors in organ transplantations. The major HLA antigens are essential elements for immune function. Different classes have different functions: HLA class I antigens (A, B & C) present peptides from inside the cell (including viral peptides if present). These peptides are produced from digested proteins that are broken down in the proteasomes. The peptides are generally small polymers, about 9 amino acids in length. Foreign antigens attract killer T-cells (also called CD8 positive- or cytotoxic T-cells) that destroy cells.
Immunogen: HLA Class 1 Antigen-A2,A28. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HLA-An are readily searchable from our website. Different antibodies against the same target such as HLA-A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. HLA-An also interacts with the following gene(s): B2M, DEK, ERBB2, KIR3DL2, LILRB1, LILRB2, MAGEA1, MAGEA4, SRC, nef.