anti-Helicobacter pylori Urease, Large Subunit Antigen antibody product blog
Tags: Antibody; Monoclonal Antibody; Helicobacter pylori Urease, Large Subunit Antigen; anti-Helicobacter pylori Urease, Large Subunit Antigen antibody;
The Helicobacter pylori Urease, Large Subunit Antigen n/a (Catalog #MBS603390) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Helicobacter pylori Urease, Large Subunit Antigen can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:16,000
Western Blot: 1:8000. Researchers should empirically determine the suitability of the Helicobacter pylori Urease, Large Subunit Antigen n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
H. pylori produces large amounts of the enzyme urease, molecules of which are localized inside and outside of the bacterium. Urease breaks down urea (which is normally secreted into the stomach) to carbon dioxide and ammonia. The ammonia is converted to ammonium by accepting a proton (H+), which neutralizes gastric acid. The survival of H. pylori in the acidic stomach is dependent on urease. The ammonia produced is toxic to the epithelial cells, and along with the other products of H. pylori�including proteases, vacuolating cytotoxin A (VacA), and certain phospholipases, damages those cells.
Immunogen: Recombinant H. pylori Urease large subunit (60kD). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Helicobacter pylori Urease, Large Subunit Antigen are readily searchable from our website. Different antibodies against the same target such as Helicobacter pylori Urease, Large Subunit Antigen may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.