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anti-HAVCR1 antibody product blog

Posted on 2013-07-20 05:42:10 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-HAVCR1 antibody; HAVCR1; HAVCR1 / KIM-1;
The HAVCR1 havcr1 (Catalog #MBS241834) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human HAVCR1 / KIM-1 reacts with Human, Mouse
Predicted Reactivity: Gorilla, Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s HAVCR1 / KIM-1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB).
IHC-P (2.5 - 5 ug/ml), WB (1 - 3 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the HAVCR1 havcr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The HAVCR1 havcr1 product has the following accession number(s) (GI #153085427) (NCBI Accession #NP_036338.2) (Uniprot Accession #Q96D42). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal (IgG) to Human HAVCR1 / KIM-1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-TIM-1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (IHC) HAVCR1.

Western Blot (WB) (Western blot of HAVCR1/TIM-1 in human brain lysate in the A) absence and B) presence of immunizing peptide, and C) mouse brain lysate.)
Western Blot (WB) HAVCR1.

Hepatitis A Virus Cellular Receptor 1 (HAVCR1) is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. HAVCR1 may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals.

Target Species: Human
Immunogen Description: A synthetic peptide (SPLYSYTTDGNDTVT) of human HAVCR1/TIM-1protein were used as immunogen. This sequence corresponds to amino acids (aa) 248-262 of NP_036338 and aa 84-98 of EAW61615.1. Isoforms of HAVCR1/TIM-1 have been described. Immunogen Type: Synthetic peptide
Immunogen: HAVCR1 / KIM-1 antibody was raised against a synthetic peptide (SPLYSYTTDGNDTVT) of human HAVCR1/TIM-1protein were used as immunogen. This sequence corresponds to amino acids (aa) 248-262 of NP_036338 and aa 84-98 of EAW61615.1. Isoforms of HAVCR1/TIM-1 have been described. For example, NP_036338 is 364 aa and EAW61615.1 is 194 aa. EAW61615.1 is referred to as isoform CRA_a. Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey (93%); Dog (80%).
Antigen Modification: aa200-300. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing HAVCR1 are readily searchable from our website. Different antibodies against the same target such as HAVCR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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