anti-GYPA antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-GYPA antibody; GYPA; Glycophorin A;
The GYPA gypa (Catalog #MBS524005) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-human Glycophorin A, FITC (Polyclonal) (rabbit IgG) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Glycophorin A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the GYPA gypa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The GYPA gypa product has the following accession number(s) (GI #386760) (NCBI Accession #AAA52768.1) (Uniprot Accession #P02724). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-human Glycophorin A, FITC (Polyclonal) (rabbit IgG) with the following immunoassay(s):
Testing Data
anti-human Glycophorin A (GpA) Polyclonal Antibody targets the human Glycophorin A protein. This 131 amino acid, 16 KDa, transmembrane sialoglycoprotein spans the membrane of erythrocytes once and exists predominantly as a homodimer. GpA presents its N terminus at the extracellular surface of the human red blood cell, has a single transmembrane domain and an internal cytoplasmic C terminus. GpA contributes to the expression of blood group antigen M and N specificities, which work to prevent red blood cell aggregation in circulation. Studies show that GpA is expressed early on the cell surface during erythropoiesis as pluripotent stem cells are recruited to differentiate into erythrocytes. This makes GpA an useful marker for studying the developmental biology of hematopoietic progenitor cells. This FITC conjugated polyclonal antibody recognizes various epitopes on the GpA protein. This antibody has been reported to work primarily in flow cytometry. The 23 residue hydrophobic transmembrane domain has been shown to mediate non-covalent dimerization of the protein under conditions of SDS page (and in other detergents). We also sell a purified version of this antibody (CL8020AP).
Immunogen: Human Glycophorin A transmembrane protein
Donor: Rabbit serum. Presentation: 100 ug FITC conjugated Ig buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing GYPA are readily searchable from our website. Different antibodies against the same target such as GYPA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.