|The FN1 fn1 (Catalog #MBS175011) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Fibronectin antibody (monoclonal) reacts with Human, Chicken, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Fibronectin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin, Immunocytochemistry ICC. Researchers should empirically determine the suitability of the FN1 fn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FN1 fn1 product has the following accession number(s) (GI #300669710) (NCBI Accession #P02751.4) (Uniprot Accession #P02751). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Description: Mouse IgG monoclonal antibody for Fibronectin, fibronectin 1 (FN1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, mouse, rat, chicken. No cross reactivity with other proteins. Uniprot ID: P02751
Background: Fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Cellular fibronectin is a 550KDa glycoprotein existing as two heterodimers, different from plasma fibronectin in the presence of additional polypeptide segments and in altering morphology of transformed cells and hemaglutination.
Immunogen: Fibronectin from human plasma. Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FN1 are readily searchable from our website. Different antibodies against the same target such as FN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Connective Tissue, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. Carcinoma, Cardiovascular Diseases, Diabetes Mellitus, Fibrosis, Inflammation, Kidney Diseases, Liver Diseases, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to Anti-Fibronectin antibody (monoclonal).