anti-FKBP15 antibody product blog
Tags: Antibody; Polyclonal Antibody; FKBP15; anti-FKBP15 antibody;
The FKBP15 fkbp15 (Catalog #MBS150935) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FKBP15 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s FKBP15 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).FKBP15 antibody can be used for detection of FKBP15 by Western blot at 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the FKBP15 fkbp15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FKBP15 fkbp15 product has the following accession number(s) (GI #150010552) (NCBI Accession #NP_056073) (Uniprot Accession #Q5T1M5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FKBP15 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of FKBP15 in 3T3 cell lysate with FKBP15 antibody at 1 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of FKBP15 in mouse brain tissue with FKBP15 antibody at 2.5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of FKBP15 in mouse brain tissue with FKBP15 antibody at 20 μg/mL.)
FKBP15 Antibody: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons; overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.
Conjugate: Unconjugated
Immunogen: FKBP15 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FKBP15.
Buffer: FKBP15 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FKBP15 are readily searchable from our website. Different antibodies against the same target such as FKBP15 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.