anti-FIGF antibody product blog
Tags: Antibody; Polyclonal Antibody; VEGFD; anti-FIGF antibody; FIGF;
The FIGF figf (Catalog #MBS175354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-VEGFD antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s VEGFD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the FIGF figf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The FIGF figf product has the following accession number(s) (GI #17367984) (NCBI Accession #O43915.1) (Uniprot Accession #O43915). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-VEGFD antibody with the following immunoassay(s):
Western Blot (WB) (Anti-VEGFD antibody, MBS175354, Western blotting
Lane 1: SW620 Cell Lysate
Lane 2: COLO320 Cell Lysate
Lane 3: 6T-CEM Cell Lysate
Lane 4: HT1080 Cell Lysate
)
Description: Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D(FIGF) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: C-fos induced growth factor(FIGF)(or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al.(1997) symbolized VEGFD, was expressed as a 2.2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al.(1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al.(2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human VEGFD (101-115aa VIDEEWQRTQCSPRE), identical to the related rat and mouse sequences. Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FIGF are readily searchable from our website. Different antibodies against the same target such as FIGF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.