anti-FGF4 antibody product blog
Tags: Antibody; Polyclonal Antibody; FGF4; anti-FGF4 antibody;
The FGF4 fgf4 (Catalog #MBS150052) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FGF4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s FGF4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF).FGF4 antibody can be used for detection of FGF4 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunocytochemistry starting at 2.5 mug/mL. For immunofluorescence start at 2.5 mug/mL. Researchers should empirically determine the suitability of the FGF4 fgf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FGF4 fgf4 product has the following accession number(s) (GI #122750) (NCBI Accession #P08620.1) (Uniprot Accession #P08620). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the FGF4 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 and (B) 1 μg/mL.)
Immunocytochemistry (IHC) (Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 μg/mL.)
FGF4 Antibody: Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
Conjugate: Unconjugated
Immunogen: FGF4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of the human FGF4.
Buffer: FGF4 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FGF4 are readily searchable from our website. Different antibodies against the same target such as FGF4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.