anti-FGF2 antibody product blog
Tags: Antibody; FGF2; Monoclonal Antibody; anti-FGF2 antibody; Fibroblast Growth Factor 2, Basic, Neutralizing;
The FGF2 fgf2 (Catalog #MBS608204) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Fibroblast Growth Factor 2, Basic, Neutralizing (FGF2b) (BSA, Azide, Glycerol Free) reacts with Bovine, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Fibroblast Growth Factor 2, Basic, Neutralizing can be used in a range of immunoassay formats including, but not limited to, Neutralization.Suitable for use in Neutralization. Not suitable for Western Blot, use F4210-21 Fibroblast Growth Factor 2, Basic (FGF2b).
Dilution: Neutralization of bFGF Activity Assay: 2.5ug/ml
Neutralizes >40% growth of bovine capillary endothelial cells simulated with 5ng/ml of FGF-2/bFGF. Researchers should empirically determine the suitability of the FGF2 fgf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FGF2 fgf2 product has the following accession number(s) (GI #119625627) (Uniprot Accession #P09038). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
bFGF (FGF-2) is a member of a family of seven peptides that are potent regulators of cell proliferation, differentiation and function. bFGF stimulates the proliferation of cells of mesodermal origin and many cells of endodermal, ectodermal and neuroectodermal origin. bFGF also induces neuron differentiation, survival and regeneration and stimulates astrocyte migration. bFGF may also be involved in the production of a variety of pathological conditions arising from excessive cell proliferation.
Immunogen: Purified bovine brain basic FGF (HBGF-2). MW:17.5kD. Positive Control: fetal liver or kidney tissue. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FGF2 are readily searchable from our website. Different antibodies against the same target such as FGF2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Bone, Bone Marrow, Brain, Connective Tissue, Embryonic Tissue, Eye, Heart, Muscle, Skin, Vascular tissues are correlated with this protein. FGF2 also interacts with the following gene(s): CD44, FGFBP1, FGFR1, FGFR3, FGFR4, PF4, PTX3, SDC1, SDC2, SDC3. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Fibrosis, Inflammation, Myocardial Ischemia, Neoplasms, Neoplasms, Experimental, Neovascularization, Pathologic, Vascular Diseases are some of the diseases may be linked to Fibroblast Growth Factor 2, Basic, Neutralizing (FGF2b) (BSA, Azide, Glycerol Free).