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anti-FBG4 antibody product blog

Posted on 2015-05-13 03:46:33 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; FBG4; anti-FBG4 antibody;
The FBG4 fbxl4 (Catalog #MBS536012) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FBG4 antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s FBG4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500-1:1,000. Researchers should empirically determine the suitability of the FBG4 fbxl4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The FBG4 fbxl4 product has the following accession number(s) (GI #18859805) (NCBI Accession #NP_572951.1) (Uniprot Accession #Q9VY46). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Affinity purified Rabbit polyclonal FBG4 antibody.

FBG4 fbxl4

Biological Significance: F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: FBG4 antibody was raised in rabbit using residues 70-85 (LQLARDRSAEGRALYA) of the human FBG4 protein as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FBG4 are readily searchable from our website. Different antibodies against the same target such as FBG4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Atrophy, Nervous System Diseases are some of the diseases may be linked to FBG4 antibody.
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