anti-FAAH antibody product blog
Tags: Antibody; Polyclonal Antibody; Fatty Acid Amide Hydrolase; anti-FAAH antibody; FAAH;
The FAAH faah (Catalog #MBS614482) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Fatty Acid Amide Hydrolase (FAAH) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Fatty Acid Amide Hydrolase can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1-10ug/ml (using Chemiluminescence technique).
ELISA: 1:10,000-1:50,000 using 50-100ng F0019-68A control peptide/well. Researchers should empirically determine the suitability of the FAAH faah for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FAAH faah product has the following accession number(s) (GI #4249693) (Uniprot Accession #O00519). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Cannabinoids, a group of C21 compounds present in Cannabis sativa L., their carboxylic acids, analogs, and transformation products, are the active ingredients found in hasish and marihuana. (-)-trans-D9-tetrahydrocannabinol (D9-THC) is the major psychopharmacologically active component of Cannabis. Cannabis affects cognition and memory, euphoria and sedation, and antinociception (analgesia) without the respiratory depression problems associated with opioid analgesics. To date, two sub-types of the G-protein coupled cannabinoid receptor, CB1 and CB2, have been identified. The first brain-derived endogenous cannabinoids, an unsaturated fatty-acid ethanolamide, arachidonylethanolamide (AEA, also called anandamide) was found in brain. AEA has higher affinity for the CB1 than for the CB2. Neurons and astrocytes have been found to re-uptake and hydrolyse anandamide rapidly, resulting in the formation of arachidonic acid and ethanolamine. The uptake mechanism has been shown to be mediated by a saturable, selective, temperature-dependent and Na+-independent transporter. Anandamide hydrolysis is catalyzed by a membrane-bound amidohydrolase (called anandamide amidohydrolase or fatty acid amide hydrolase, FAAH). FAAH (rat/mouse/human 579aa; chromosome 1p34-p35; mol wt ~67 kD) sequence analyses suggest a single predicted transmembrane domain at the extreme N-terminus of the enzyme.
Immunogen: A 17 amino acid peptide sequence near the N-terminus of human FAAH (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FAAH are readily searchable from our website. Different antibodies against the same target such as FAAH may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.