anti-F5 antibody product blog
Tags: Antibody; Monoclonal Antibody; anti-F5 antibody; Factor V, activation peptide, 120kD;
The F5 f5 (Catalog #MBS606434) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Factor V, activation peptide, 120kD reacts with Bovine and may cross-react with other species as described in the data sheet. MyBioSource\'s Factor V, activation peptide, 120kD can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Radioimmunoassay (RIA).Suitable for use in RIA, ELISA and Western Blot.
Dilution: Western Blot: 5ug/ml. Researchers should empirically determine the suitability of the F5 f5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The F5 f5 product has the following accession number(s) (GI #182798) (Uniprot Accession #P12259). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Factor V is a large, single chain, plasma glycoprotein which is an essential component in the blood coagulation cascade. During coagulation, the procofactor, factor V, is converted to the active cofactor, factor Va, via limited proteolysis by the serine protease a-thrombin, and less efficiently by factor Xa. The active cofactor is composed of an NH2-terminal derived heavy chain (Mr=94,000) and a COOH-terminal derived light chain (Mr=74,000) which remain non-covalently associated in the presence of calcium ions. Factor Va serves as a cofactor for the serine protease factor Xa. Factor Va and Xa assemble on a phospholipid surface in a non-covalent and calcium ion-dependent manner, to form the prothrombinase complex. The prothrombinase complex is responsible for the rapid conversion of the zymogen prothrombin to the active serine protease, a-thrombin. Assembly of the prothrombinase complex increases the rate at which prothrombin is converted to thrombin by nearly 300,000-fold relative to the rate with factor Xa alone. Down regulation of the prothrombinase complex is accomplished partly through the inactivation of factor Va by activated protein C.
Immunogen: Purified Bovine Factor V. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing F5 are readily searchable from our website. Different antibodies against the same target such as F5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. F5 also interacts with the following gene(s): F10, PROC.