anti-ERK1/2 (P44-MAPK) antibody product blog
Tags: Antibody; Polyclonal Antibody; ERK1/2 (P44-MAPK); anti-ERK1/2 (P44-MAPK) antibody;
The ERK1/2 (P44-MAPK) n/a (Catalog #MBS462164) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti ERK1/2 Polyclonal antibody reacts with Human, Mouse, Rat, Chicken, Canine and may cross-react with other species as described in the data sheet. MyBioSource\'s ERK1/2 (P44-MAPK) can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot, Immunohistochemistry.Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml. Researchers should empirically determine the suitability of the ERK1/2 (P44-MAPK) n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ERK1/2 (P44-MAPK) n/a product has the following accession number(s) (GI #1169549). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti ERK1/2 Polyclonal antibody with the following immunoassay(s):
Testing Data
The extracellular signal-regulated kinases � (ERK1/2) are also known as MAPK (Mitogen-activated protein kinases) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (ERK1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the identification and treatment of cancer. The phosphorylation of MAPK at Thr202 and Tyr 204 are correlated to the progression and metastatic potential of tumor cells.
Antigen Preparation: A synthetic peptide derived from internal sequence of ERK1/2 protein from human, rat, mouse and dog origins. Positive Control: 3T3 cells
Cellular Location: Cytoplasmic. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ERK1/2 (P44-MAPK) are readily searchable from our website. Different antibodies against the same target such as ERK1/2 (P44-MAPK) may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Brain, Connective Tissue, Ear, Embryonic Tissue, Heart, Kidney, Muscle, Umbilical Cord, Vascular tissues are correlated with this protein. ERK1/2 (P44-MAPK) also interacts with the following gene(s): FLNA. The following patways have been known to be associated with this gene.