anti-EHI_118260 antibody product blog
Tags: Antibody; Polyclonal Antibody; diaphanous homolog 1; anti-EHI_118260 antibody; EHI_118260;
The EHI_118260 ehi_118260 (Catalog #MBS714432) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human diaphanous homolog 1 (Drosophila) polyclonal Antibody reacts with Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology. and may cross-react with other species as described in the data sheet. MyBioSource\'s diaphanous homolog 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF).ELISA; Use at an assay dependent dilution.
WB: 1:1000-1:10000
IF: 1:10-1:100 (Recommender dilutions)
Positive WB detected in: HeLa cells, COS-7 cells, human heart tissue, human skeletal muscle tissue, NIH/3T3 cells
Positive IF detected in : HepG2 cells, Hela cells. Researchers should empirically determine the suitability of the EHI_118260 ehi_118260 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EHI_118260 ehi_118260 product has the following accession number(s) (GI #67481361) (NCBI Accession #XP_656030.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Rabbit polyclonal to DIAPH1
Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration By similarity. Has neurite outgrowth promoting activity By similarity. In hear cells, it may play a role in the regulation of actin polymerization in hair cells. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Immunogen: Human DIAP1
Conjugate : Non-conjugated. Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10886 / sc-10885 / sc-10888 / sc-28775. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EHI_118260 are readily searchable from our website. Different antibodies against the same target such as EHI_118260 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.