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anti-EGFR antibody product blog

Posted on 2014-03-29 13:56:08 by mybiosource_staff
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Tags: Antibody; anti-EGFR antibody; EGFR; Polyclonal Antibody;
The EGFR egfr (Catalog #MBS857230) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The EGFR (Phospho-Tyr1172) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s EGFR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
WB: 1:500~1:1000
IHC: 1:50~1:100. Researchers should empirically determine the suitability of the EGFR egfr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The EGFR egfr product has the following accession number(s) (GI #29725609) (NCBI Accession #NP_005219.2) (Uniprot Accession #P00533). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the EGFR (Phospho-Tyr1172) Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (P-Peptide-+ Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using EGFR (phospho-Tyr1172) antibody.)
Immunohistochemistry (IHC) EGFR.

Western Blot (WB) (Western blot analysis of extract from A431 cell untreated or treated with EGF (200ng/ml, 5min), using EGFR (Ab-1172) antibody and EGFR (phospho-Tyr1172) antibody.)
Western Blot (WB) EGFR.

Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine 1172 (P-D-YP-Q-Q). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing EGFR are readily searchable from our website. Different antibodies against the same target such as EGFR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Disease Progression, Kidney Diseases, Lung Neoplasms, Neoplasms, Small Cell Lung Carcinoma are some of the diseases may be linked to EGFR (Phospho-Tyr1172) Antibody. Brain, Heart, Kidney, Liver, Lung, Muscle, Prostate, Skin, Stomach, Vascular tissues are correlated with this protein. EGFR also interacts with the following gene(s): CBL, CTNNB1, EGF, ERBB2, ERBB3, ERBB4, GRB2, MAPK1, MET, STAT3.
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