anti-DLC1 antibody product blog
Tags: Antibody; Polyclonal Antibody; DLC1; anti-DLC1 antibody;
The DLC1 dlc1 (Catalog #MBS421454) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-DLC1 (Isoforms 1 and 3) Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Pig and may cross-react with other species as described in the data sheet. MyBioSource\'s DLC1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB).Peptide ELISA: Antibody detection limit dilution 1: 32000.
Immunohistochemistry: In paraffin embedded Human Adrenal Gland (Medulla) shows strong reticulate staining in the cytoplasm of medular cells. Recommended concentration, 5ug/ml.
Western Blot: This antibody has been successfully used in WB for human heart as described in the following paper: Ko et al, Liver Int.2010 Jan;30(1): 139-48.; PMID: 19874489. Researchers should empirically determine the suitability of the DLC1 dlc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DLC1 dlc1 product has the following accession number(s) (GI #256017148) (NCBI Accession #NP_872584.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
SVAIRKRSWE EHC.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat anti-DLC1 (Isoforms 1 and 3) Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) ((5ug/ml) staining of paraffin embedded Human Adrenal Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.)
Immunogen: Peptide with sequence SVAIRKRSWEEHC, from the N Terminus of the protein sequence according to NP_872584.2; NP_079043.3.
Epitope: N Terminus. Note: This antibody is expected to recognise isoforms 1 and 3 (NP_872584.2 and NP_079043.3 resp) but NOT isoform 2 (NP_006085.2). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DLC1 are readily searchable from our website. Different antibodies against the same target such as DLC1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Nerve, Prostate, Skin, Stomach tissues are correlated with this protein. The following patways have been known to be associated with this gene. DLC1 also interacts with the following gene(s): CDC42, PLCD1, RHOA, RHOB, RHOC, TENC1, TNS1, TNS3. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Hepatocellular, Liver Diseases, Liver Neoplasms, Liver Neoplasms, Experimental, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to Goat anti-DLC1 (Isoforms 1 and 3) Antibody.