anti-DDC antibody product blog
Tags: Antibody; DDC; Polyclonal Antibody; anti-DDC antibody; DOPA Decarboxylase, Human;
The DDC ddc (Catalog #MBS502021) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-DOPA Decarboxylase reacts with Bovine, canine, guinea pig, human, rabbit, rat and sheep tissues and may cross-react with other species as described in the data sheet. MyBioSource\'s DOPA Decarboxylase, Human can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Quality Control: Western blots performed on each lot.
WB: 1:1000. Researchers should empirically determine the suitability of the DDC ddc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DDC ddc product has the following accession number(s) (GI #4503281) (NCBI Accession #NP_000781.1) (Uniprot Accession #P20711). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-DOPA Decarboxylase with the following immunoassay(s):
Testing Data
Affinity purified rabbit polyclonal antibody.
Antigen: Peptide from N-terminus region of human DOPA decarboxylase (DDC), conjugated to keyhole limpet hemocyanin (KLH).
Immunogen Information: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Immunogen Species: Human. Species Reactivity Note: The antibody has been directly tested for reactivity in Western blots in bovine, canine, guinea pig, human, rabbit, rat and sheep tissues.
Biological Significance: DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson\'s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DDC are readily searchable from our website. Different antibodies against the same target such as DDC may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Eye, Intestine, Kidney, Liver, Lung, Nerve, Pancreas, Prostate tissues are correlated with this protein. Brain Diseases, Death, Disease Models, Animal, Liver Diseases, Mental Disorders, Movement Disorders, Necrosis, Neoplasms, Parkinsonian Disorders, Poisoning are some of the diseases may be linked to Anti-DOPA Decarboxylase.