anti-DBI antibody product blog
Tags: Antibody; Monoclonal Antibody; Diazepam Binding Inhibitor; DBI; anti-DBI antibody;
The DBI dbi (Catalog #MBS609259) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Diazepam Binding Inhibitor (DBI, Acyl-CoA-binding Protein, ACBP, Endozepine, EP) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Diazepam Binding Inhibitor can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunoprecipitation (IP).Suitable for use in ELISA and Immunoprecipitation.
Dilution: Immunoprecipitation: 1-2ul/400ul lysates. Researchers should empirically determine the suitability of the DBI dbi for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The DBI dbi product has the following accession number(s) (GI #181478) (Uniprot Accession #P07108). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Diazepam Binding Inhibitor (DBI) is a highly conserved 10kD polypeptide which is expressed in various species range from yeast to mammals. As an inverse agonist for benzodiazepine receptors, DBI downregulates inhibitory effects of GABA. It also has potential to induce anxiety. Found in central andperipheral tissues, DBI also participates in metabolism of steroids, which has been known to partially modify GABAA receptor function in the CNS. In peripheral tissues, DBI plays regulatory roles in steroidogenesis. DBI levels have been reported to be decreased in the cerebrospinal fluid obtained from patients with Alzheimer disease.
Immunogen: Recombinant human GST fusion protein purified from E.coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing DBI are readily searchable from our website. Different antibodies against the same target such as DBI may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. DBI also interacts with the following gene(s): TSPO. The following patways have been known to be associated with this gene. Adrenal Gland, Blood, Brain, Heart, Kidney, Liver, Nerve, Pancreas, Testis, Vascular tissues are correlated with this protein. Anxiety Disorders, Brain Injuries, Carcinoma, Diabetes Mellitus, Drug Toxicity, Hemorrhage, Liver Diseases, Neoplasms, Neoplasms, Experimental, Neurologic Manifestations are some of the diseases may be linked to Diazepam Binding Inhibitor (DBI, Acyl-CoA-binding Protein, ACBP, Endozepine, EP).