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anti-CYP19A1 antibody product blog

Posted on 2014-05-08 02:24:00 by mybiosource_staff
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Tags: Antibody; anti-CYP19A1 antibody; CYP19A1; Polyclonal Antibody; Aromatase/CYP19A1;
The CYP19A1 cyp19a1 (Catalog #MBS421466) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Aromatase/CYP19A1 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Aromatase/CYP19A1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB).
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 50-55kDa band observed in Human Placenta lysates (calculated MW of 57.9kDa according to NP_000094.2 and NP_112503.1). Recommended concentration: 0.1-0.3ug/ml. Researchers should empirically determine the suitability of the CYP19A1 cyp19a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CYP19A1 cyp19a1 product has the following accession number(s) (GI #13904858) (NCBI Accession #NP_000094.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat anti-Aromatase/CYP19A1 Antibody with the following immunoassay(s):
Western Blot (WB) ((0.1ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB) CYP19A1.

Immunogen: Peptide with sequence C-HDLSLHPDETKN, from the internal region of the protein sequence according to NP_000094.2; NP_112503.1.
Epitope: Internal region. Note: This antibody is expected to recognise both reported isoforms (NP_000094.2 and NP_112503.1), which are identical. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CYP19A1 are readily searchable from our website. Different antibodies against the same target such as CYP19A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Breast Neoplasms, Cardiovascular Diseases, Endometriosis, Hyperplasia, Infertility, Female, Neoplasms, Experimental, Osteoporosis, Ovarian Diseases, Polycystic Ovary Syndrome are some of the diseases may be linked to Goat anti-Aromatase/CYP19A1 Antibody. Adrenal Gland, Blood, Brain, Embryonic Tissue, Liver, Lung, Ovary, Placenta, Testis, Vascular tissues are correlated with this protein. CYP19A1 also interacts with the following gene(s): FOXL2, HSD17B1, HSD17B2, HSD17B3, HSD17B6, HSD17B7, HSD3B1, HSD3B2, NR5A1, SRD5A1.
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