anti-CXCL12 antibody product blog
Tags: Antibody; Stromal Cell Derived Factor 1alpha; Polyclonal Antibody; CXCL12; anti-CXCL12 antibody;
The CXCL12 cxcl12 (Catalog #MBS619671) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Stromal Cell Derived Factor 1alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Stromal Cell Derived Factor 1alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:1000
Immunohistochemistry: 1:100-1:500. Researchers should empirically determine the suitability of the CXCL12 cxcl12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CXCL12 cxcl12 product has the following accession number(s) (GI #40316924) (NCBI Accession #NP_954637.1) (Uniprot Accession #Q6ICW0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
SDF-1a (stromal cell-derived factor-a), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.
Immunogen: E. coli-expressed mouse SDF-1a. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CXCL12 are readily searchable from our website. Different antibodies against the same target such as CXCL12 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Bone, Bone Marrow, Brain, Embryonic Tissue, Heart, Liver, Lung, Muscle, Spleen, Vascular tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Cardiovascular Diseases, Inflammation, Leukemia, Lymphoma, Myocardial Ischemia, Necrosis, Neoplasm Metastasis, Neoplasms are some of the diseases may be linked to Stromal Cell Derived Factor 1alpha (SDF1 alpha, SDF1a, SDF-1a, Chemokine (C-X-C Motif) Ligand 12, CXCL12, hIRH, Pre-B cell Growth-stimulating Factor, PBSF, SCYB12, TLSF-a, TPAR1).