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anti-ctxB antibody product blog

Posted on 2014-08-02 06:29:53 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; anti-ctxB antibody; ctxB; CHOLERA TOXIN;
The Cholera Toxin ctxb (Catalog #MBS430005) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Cholera Toxin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Sandwich Immunoassay.
EIA (coating), B-subunit of CT. Researchers should empirically determine the suitability of the Cholera Toxin ctxb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Cholera Toxin ctxb product has the following accession number(s) (GI #808902) (NCBI Accession #BAA06291.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Description: Anti-Cholera Toxin B Subunit
Mouse anti-cholera toxin (beta-subunit) monoclonal antibody
Introduction: Cholera toxin is a protein complex secreted by the bacterium Vibrio cholerae. The cholera toxin is an oligomeric complex made up of six protein subunits: a single copy of the A subunit (part A, enzymatic), and five copies of the B subunit (part B, receptor binding), denoted as AB5. B subunits bind and internalize A subunits, which are processed to A1. The A1 form catalyses ADP ribosylation from NAD to the regulatory component of adenylate cyclase, thereby activating it. Increased adenylate cyclase activity increases cyclic AMP (cAMP) synthesis causing massive fluid and electrolyte efflux, resulting in diarrhoea.

Cholera Toxin ctxb

Usage: This product does not contain livestock or poultry disease agents, non-toxic/non contagious and is not intended for human use, only for laboratory research and development.
Immunogen: Purified beta-subunit of cholera toxin. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Cholera Toxin are readily searchable from our website. Different antibodies against the same target such as Cholera Toxin may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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