anti-CTSL1 antibody product blog
Tags: Antibody; Cathepsin L; Monoclonal Antibody; anti-CTSL1 antibody; CTSL1;
The CTSL1 ctsl (Catalog #MBS140225) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Cathepsin L can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).Cathepsin-L antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~2,000. Recommended starting dilution is 1:1,000. Researchers should empirically determine the suitability of the CTSL1 ctsl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CTSL1 ctsl product has the following accession number(s) (GI #384081592) (NCBI Accession #NP_001244900.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Introduction: Cathepsins B, C, H, L, S, V, X/Z/P and 1 are cysteine proteases of the papain family. Cathepsin C is also known as DPPI (dipeptidyl-peptidase I). Cathepsin An is a serine carboxypeptidase and Cathepsin D and E are aspartic proteases. As lysosomal proteases, cathepsins play an important role in protein degradation. Because of their redistribution or increased levels in human and animal tumors, cathepsins may have a role in invasion and metastasis. Cathepsins are synthesized as inactive proenzymes and processed to become mature and active enzymes. Endogenous protein inhibitors, such as cystatins and some serpins, inhibit active enzymes.
Immunogen: Anti-human Cathepsin-L mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Cathepsin-L amino acids 114-333 purified from E Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CTSL1 are readily searchable from our website. Different antibodies against the same target such as CTSL1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. CTSL1 also interacts with the following gene(s): CD74, CST3, CSTA, CTSS, IFI30. Blood, Bone, Brain, Kidney, Liver, Lung, Muscle, Skin, Spleen, Testis tissues are correlated with this protein. Cardiovascular Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Liver Diseases, Necrosis, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases, Proteinuria are some of the diseases may be linked to Mouse Anti Human Cathepsin L.