|The COL6A1 col6a1 (Catalog #MBS631249) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The COL6A1, CT (Collagen alpha-1(VI) Chain) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s COL6A1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100. Researchers should empirically determine the suitability of the COL6A1 col6a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The COL6A1 col6a1 product has the following accession number(s) (GI #87196339) (NCBI Accession #NP_001839.2) (Uniprot Accession #P12109). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Immunogen: Synthetic peptide selected from the C-terminal region of human COL6A1 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing COL6A1 are readily searchable from our website. Different antibodies against the same target such as COL6A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adipose Tissue, Blood, Bone, Brain, Connective Tissue, Heart, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. Abnormalities, Multiple, Bethlem myopathy, Congenital Abnormalities, Genetic Diseases, Inborn, Mental Retardation, Neoplasm Metastasis, Neoplasms, Neurologic Manifestations, Ossification of Posterior Longitudinal Ligament, ULLRICH CONGENITAL MUSCULAR DYSTROPHY are some of the diseases may be linked to COL6A1, CT (Collagen alpha-1(VI) Chain). COL6A1 also interacts with the following gene(s): COL2A1.