anti-COL4A5 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-Col4a5 antibody; Col4a5; Collagen Type IV;
The COL4A5 col4a5 (Catalog #MBS534314) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Collagen Type IV antibody reacts with Cat, Dog, Fish, Human, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Collagen Type IV can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB).IHC: 1:50-1:100. Researchers should empirically determine the suitability of the COL4A5 col4a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The COL4A5 col4a5 product has the following accession number(s) (GI #4261609) (NCBI Accession #AAD13909.1) (Uniprot Accession #P29400). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Rabbit polyclonal Collagen Type IV antibody.
Biological Significance: Type-IV collagen is a type of collagen found primarily in the basal lamina. The C-terminus domain is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, type-IV lacks the regular glycine in every third residue necessary for the tight, collagen helix. This makes the overall arrangement more sloppy with kinks. These two features cause the collagen to form in a sheet, the form of the basal lamina. Cross-Reactivity: Cat, dog, fish, human, mouse, pig, rat
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: Collagen type IV antibody was raised in rabbit using human placenta type IV collagen as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing COL4A5 are readily searchable from our website. Different antibodies against the same target such as COL4A5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. COL4A5 also interacts with the following gene(s): COL18A1, COL1A1, COL1A2, COL4A2, COL4A3, COL4A4, COL4A6. Bone, Brain, Ear, Embryonic Tissue, Eye, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. ALPORT SYNDROME, X-LINKED, Autoimmune Diseases, Disease Models, Animal, Fibrosis, Hearing Loss, Sensorineural, Heart Defects, Congenital, Inflammation, Kidney Diseases, Lung Diseases, Proteinuria are some of the diseases may be linked to Collagen Type IV antibody.