anti-CLU antibody product blog
Tags: Antibody; Clusterin; CLU; Monoclonal Antibody; anti-Clu antibody;
The CLU clu (Catalog #MBS531752) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Clusterin antibody (alpha chain) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Clusterin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB).IHC: 5 ug/ml. Researchers should empirically determine the suitability of the CLU clu for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CLU clu product has the following accession number(s) (GI #355594753) (NCBI Accession #NP_001822.3) (Uniprot Accession #P10909). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Clusterin antibody (alpha chain) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of HeLa cell lysate probed with anti-Clusterin alpha chain (0.5ug/ml).)
Mouse monoclonal Clusterin antibody (alpha chain).
Biological Significance: Clusterin is an ubiquitous multifunctional protein of 80 kDa comprising of two disulfide-linked subunits, alpha and beta, and capable of interacting with a broad range of molecules. It is implicated in numerous biological processes including sperm maturation, lipid transport, regulation of the complement cascade, membrane recycling, cell death, immune regulation, cell adhesion and morphological transformation. Immunogen: Clusterin antibody (alpha chain) was raised in mouse using native clusterin purified from human serum as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CLU are readily searchable from our website. Different antibodies against the same target such as CLU may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Eye, Kidney, Liver, Lung, Nerve, Prostate, Testis, Vascular tissues are correlated with this protein. CLU also interacts with the following gene(s): ALB, APP, BAX, TGFB1, TIMP1. Alzheimer Disease, Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Necrosis, Nervous System Diseases, Prostatic Neoplasms are some of the diseases may be linked to Clusterin antibody (alpha chain).