anti-CIRBP antibody product blog
Tags: Antibody; Monoclonal Antibody; CIRBP; anti-CIRBP antibody;
The CIRBP cirbp (Catalog #MBS6007311) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CIRBP (Cold-inducible RNA-binding Protein, A18 hnRNP, Glycine-rich RNA-binding Protein CIRP, A18HNRNP, CIRP) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s CIRBP can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA, Immunoflourescence and Western Blot. Other applications not tested. Researchers should empirically determine the suitability of the CIRBP cirbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The CIRBP cirbp product has the following accession number(s) (GI #4502847) (NCBI Accession #NP_001271.1) (Uniprot Accession #Q14011). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MASDEGKLFV GGLSFDTNEQ SLEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the CIRBP (Cold-inducible RNA-binding Protein, A18 hnRNP, Glycine-rich RNA-binding Protein CIRP, A18HNRNP, CIRP) with the following immunoassay(s):
Western Blot (WB) (Western Blot detection against Immunogen (35.64kD).)
Testing Data (Detection limit for recombinant GST tagged CIRBP is ~0.3ng/ml as a capture antibody.)
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3\'-untranslated regions (3\'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed.
Immunogen: Partial recombinant corresponding to aa1-90 from human CIRBP (NP_001271.1) with GST tag. MW of the GST tag alone is 26kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing CIRBP are readily searchable from our website. Different antibodies against the same target such as CIRBP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Breast Neoplasms, Carcinoma, Hepatocellular, Cardiovascular Diseases, Infertility, Male, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis, Neoplasms are some of the diseases may be linked to CIRBP (Cold-inducible RNA-binding Protein, A18 hnRNP, Glycine-rich RNA-binding Protein CIRP, A18HNRNP, CIRP).